I'd personally say just limit it to the cities. It still means Kara players might be inclined to declare for Zorai and Kami players might be inclined to declare for Matis or Tryker to get the Q250 item vendors.
The Q250 zones would be a bit of a stretch since they're not necessarily directly influenced by the civs.
The Q250 zones would be a bit of a stretch since they're not necessarily directly influenced by the civs.