My current favorite mission requires 396 materials. Q250 gen mats cost 64 nation points each, so it would require 25,344 nation points to fully compensate for the mats used. At 90% this is still 22,784 points. thats something like 4 full delivery runs, or 10 of the highest dig mission from the kitin camps if you are at 100 fame. You could dig the craft mats like 10 times for the same time invested!
